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NURS 6521N Advanced Pharmacology
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A patient will soon begin targeted therapy as a component of her treatment plan for chronic leukemia. The nurse is conducting health education about this new aspect of the patient’s drug regimen and the patient has asked about the potential side e±ects of treatment. How should the nurse best respond? Response Feedback: Targeted therapies are generally considered to be less toxic than traditional chemotherapy drugs. However, adverse reactions to targeted therapies can occur such as severe skin reactions, GI toxicities, skin reactions, and thrombosis. Question 2 1 out of 1 points Mr. Singh is a 66-year-old man who is receiving chemotherapy for the treatment of lung cancer that has metastasized to his liver. In an e±ort to prevent infection, Mr. Singh has been prescribed ²lgrastim (Neupogen). Which of the nurse’s following assessment questions most directly addresses a common adverse e±ect of ²lgrastim? Response Feedback : Medullary bone pain is a consistently observed adverse e±ect that can be attributed to drug therapy with ²lgrastim; it is mild to moderate in severity and is reported in 56% of patients taking the drug. Shortness of breath, mucosal bleeding, and cool, clammy skin are not adverse e±ects typical of ²lgrastim. Question 3 1 out of 1 points An older adult woman has been diagnosed with acute lymphoblastic leukemia (ALL) and her care team has identi²ed potential bene²ts of imatinib. Which of the following characteristics of this patient’s current health status may preclude the use of imatinib?
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Response Feedback : Imatinib may be associated with edema. Patients should be weighed regularly and assessed for signs of ±uid retention that could be severe. The risk of edema increases with higher doses of imatinib and age greater than 65 years. Previous strokes, orthopedic surgery, or well-controlled diabetes may not contraindicate the use of imatinib. Question 4 1 out of 1 points An oncology nurse is reviewing the pathophysiology of cancer and is discussing with a colleague the factors that contribute to the success or failure of a patient’s chemotherapy. Which of the following cancerous cells is most susceptible to the e²ects of chemotherapeutic drugs? Response Feedback : Cells that have a short generation time or rapid mitotic rate are most sensitive to antineoplastic agents. All cells (both cancerous and noncancerous) have a blood supply. A lack of contact inhibition is characteristic of cancer, but this is not associated with susceptibility to chemotherapeuti…………………..
